ABSTRACT
The emergence of the novel coronavirus SARS-CoV-2 has significantly impacted the world's population, disrupting healthcare systems around the globe and leading to human and material losses. While different vaccines have been approved in record time, there continues to be a high number of daily new cases, and patients face a wide range of presentations of the disease, from asymptomatic to potentially fatal. Therefore, the search for therapeutic agents that can aid in the management and control of the disease has become one of the main goals for researchers and clinicians. As an inflammatory disease, targets for the treatment of COVID-19 have largely involved the immune system. Inflammation has also been associated with mental health disorders, and studies have shown the potential involvement of inflammatory pathways in the pathophysiology of depression. As a consequence, the hypothesis of using antidepressants and other psychotropics for the treatment of COVID-19 has emerged. In this review, we aim to summarize the molecular pathways that could be involved as well as the emergent evidence that has been reported by studies performed since the appearance of SARS-CoV-2 in 2019. While it has been observed that there are potential therapeutic pathways for the use of antidepressants in the treatment of COVID-19, additional studies are needed to evaluate the feasibility, safety, and efficacy of psychotropics in this disease.Copyright © 2023 Bentham Science Publishers.
ABSTRACT
The whole world has been affected by the pandemic generated by covid-19, creating labor problems in all professional fields. The present study is focused on the legal field in the city of Tulcan, due to the con-tention of several judicial processes.During this time many lawyers have had problems to achieve bonding with their client, so many professio-nals lost some cases because of the pandemic. In the early days of containment many of them did not have enough knowledge to be able to implement the technology in their work, to be able to achieve a trial in a correct way, as they were used to the traditional trial. Through a qualitativequantitative research, we propose results and conclusions that allow us to face possible lapses to reach effectiveness in the juridical fields.
ABSTRACT
Introduction: COVID-19 is a disease caused by the new coronavirus SARS-CoV-2, which has spread rapidly around the world. In this paper we first define the technologies of 4.0 industry used to control the pandemic. Objective: To describe the use of technology in the control of COVID-19 in Peru. Materials and methods: Systematic review of applied technologies for COVID-19 management in Peru. The revision was limited to material published in Spanish and English, preferably from indexed sources and official websites, since January 2020. Results: There are different technological solutions implemented in different countries for prevention and containment;some of them have been considered by the Peruvian government, according to the reality of technological and digital development of the country. Discussion and Conclusion: This article reviews the main Industry 4.0 technological solutions implemented around the world to appropriately manage the global health emergency. Some of these solutions, applied for pandemic control, are utilized in the strategies design by Peruvian Government;however, there are other technologies not used yet that have been identified as appropriate. In addition, some improvements in the solutions and policies are discussed, concluding that even if technology plays an important role for COVID-19 control, it is not the only factor affecting the results, as human approach and state policies are crucial for better outcomes. © 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG.